Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631019 | 0.95 | GSR (0.55) | GSRHTR2AHRH1DPP7DPP8 | |
| SCHEMBL28992842 | 0.95 | GSR (0.55) | GSRHTR2AHRH1DPP7DPP8 | |
| SCHEMBL16553896 | 0.93 | GSR (0.53) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL7533307 | 0.93 | GSR (0.53) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL2460853 | 0.89 | MDM2 (0.46) | HTR2AHRH1MDM2TDP1L3MBTL1 | |
| SCHEMBL10265227 | 0.86 | TDP1 (0.42) | HTR2AHRH1DPP7DPP8DPP9 | |
| SCHEMBL10591572 | 0.85 | POLB (0.51) | GSRMDM2TDP1LTA4HPOLB | |
| SCHEMBL9755844 | 0.85 | POLB (0.51) | GSRMDM2TDP1LTA4HPOLB | |
| Pyrophosphoric Acid SCHEMBL29018593 | 0.85 | DPP7 (0.46) | GSRDPP7DPP8DPP9MMP2 | |
| SCHEMBL6823559 | 0.84 | CES2 (0.47) | HTR2AHRH1DPP7MMP2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368903-B1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | AlliedSignal Inc. (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0368903-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE). | ALLIED SIGNAL INC (US) | 1990-05-23 | — | — | EP | disclosed |
| WO-1989000171-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | ALLIED-SIGNAL INC. (US) | 1989-01-12 | — | — | WO | disclosed |
| US-4767839-A | LIQUID CRYSTAL-FROM A DIACID AND DIESTERDIAMINE | ALLIED-SIGNAL INC. (US) | 1988-08-30 | — | — | US | disclosed |