SCHEMBL7533334

SCHEMBL7533334

O=C(Cc1ccc(O)cc1O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
MAPK1 P28482 1/20 0.54
ALOX5 P09917 1/20 0.53
MEN1 O00255 1/20 0.51
USP2 O75604 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
TYR P14679 1/20 0.48
CAMK2A Q9UQM7 1/20 0.47
TTR P02766 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28679645 0.89 TYR (0.52) ALDH1A1MAPK1GAATYR
SCHEMBL9061946 0.86 EGFR (0.49) ALDH1A1MAPK1MEN1USP2GAA
SCHEMBL6202473 0.82 POLB (0.61) ALDH1A1MAPK1MEN1KMT2A
SCHEMBL948884 0.81 AKR1B1 (0.69) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL29419312 0.81 TYR (0.60) ALDH1A1ALOX5MEN1KMT2ATYR
SCHEMBL156238 0.81 TYR (0.60) ALDH1A1ALOX5MEN1KMT2ATYR
SCHEMBL11566344 0.80 KMT2A (0.45) ALDH1A1MAPK1MEN1KMT2A
SCHEMBL11565253 0.80 LMNA (0.50) ALDH1A1MAPK1MEN1KMT2A
Hydrochloric Acid SCHEMBL28760122 0.79 AKR1B1 (0.67) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL11559415 0.79 GAA (0.54) ALDH1A1MAPK1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941992-B1 Ipriflavone preparation process ERREGIERRE SPA (IT) 2002-05-08 EP claimed
US-5973169-A Ipriflavone preparation process ERREGIERRE S.P.A. (IT) 1999-10-26 US claimed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP claimed
JP-60048924-A None JP disclosed
CN-107921171-A Wetness indicator composition comprising leuco dye 萨瓦雷I.C.股份有限公司 2018-04-17 CN disclosed
EP-0941992-B1 Ipriflavone preparation process ERREGIERRE SPA (IT) 2002-05-08 EP disclosed
EP-0615448-B1 SEX STEROID ACTIVITY INHIBITORS ENDORECH INC (CA) 2002-05-02 EP disclosed
US-5973169-A Ipriflavone preparation process ERREGIERRE S.P.A. (IT) 1999-10-26 US disclosed
US-5973169-A Ipriflavone preparation process ERREGIERRE S.P.A. (IT) 1999-10-26 US disclosed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP disclosed
EP-0941992-A1 Ipriflavone preparation process ERREGIERRE S.p.A. (IT) 1999-09-15 EP disclosed
EP-0615448-A1 SEX STEROID ACTIVITY INHIBITORS ENDORECHERCHE INC. (CA) 1994-09-21 EP disclosed
EP-0478558-B1 AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED ISOFLAVONE DERIVATIVES CHINOIN GYOGYSZER ES VEGYESZET (HU) 1994-02-02 EP disclosed
US-5247102-A Cyclization of a resorcinol derivative with ethyl orthoformate in the presence of a base CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1993-09-21 US disclosed
US-5235109-A Reacting a phenol with anhydrous aluminum chloride to form a complex, acylating, separation CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT (HU) 1993-08-10 US disclosed
WO-1993010741-A2 SEX STEROID ACTIVITY INHIBITORS ENDORECHERCHE INC. (CA) 1993-06-10 WO disclosed
EP-0478558-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED ISOFLAVONE DERIVATIVES. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1992-04-08 EP disclosed
WO-1991015483-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTITUTED ISOFLAVONE DERIVATIVES CHINOIN GYÓGYSZER ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT (HU) 1991-10-17 WO disclosed
JP-S6048924-A REMEDY FOR OSTEOPOROSIS TAKEDA CHEM IND LTD 1985-03-16 JP disclosed
US-4163746-A ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-08-07 US disclosed