SCHEMBL6202473

SCHEMBL6202473

COc1ccc(CC(=O)c2ccccc2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.61
NPC1 O15118 8/20 0.59
RAB9A P51151 7/20 0.59
KMT2A Q03164 5/20 0.59
MEN1 O00255 4/20 0.59
ALDH1A1 P00352 2/20 0.59
LMNA P02545 2/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
KDM4E B2RXH2 1/20 0.59
TP53 P04637 1/20 0.59
MAPT P10636 1/20 0.59
ALOX12 P18054 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CYP1A2 P05177 1/20 0.57
PGR P06401 1/20 0.57
CYP2D6 P10635 1/20 0.57
SLC6A2 P23975 1/20 0.57
PDE4A P27815 1/20 0.57
MAPK1 P28482 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566344 0.85 KMT2A (0.45) POLBNPC1RAB9AKMT2AMEN1
SCHEMBL11565253 0.85 LMNA (0.50) POLBNPC1RAB9AKMT2AMEN1
SCHEMBL3134578 0.85 POLB (0.58) POLBNPC1RAB9AKMT2AMEN1
SCHEMBL6849659 0.85 L3MBTL1 (0.58) NPC1RAB9AKMT2AMEN1ALDH1A1
SCHEMBL30335932 0.84 POLB (0.73) POLBNPC1RAB9AALDH1A1LMNA
SCHEMBL3296862 0.84 POLB (0.73) POLBNPC1RAB9AALDH1A1LMNA
SCHEMBL7533334 0.82 ALDH1A1 (0.54) KMT2AMEN1ALDH1A1MAPK1
SCHEMBL11568628 0.82 KAT6A (0.47) POLBNPC1RAB9AKMT2AMEN1
SCHEMBL14798106 0.81 RAB9A (0.54) POLBNPC1RAB9AKMT2AMEN1
SCHEMBL11559415 0.81 GAA (0.54) POLBNPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118845734-A Application of 2-hydroxy-4-methoxy-phenyl pentanone in preparation of medicine for treating drug-induced liver injury 陕西医药控股医药研究院有限公司 2024-10-29 CN disclosed
CN-106188982-A A kind of heat insulation aging resistance plastic building template and preparation method thereof 樊之雄 2016-12-07 CN disclosed
CN-101437579-B Antioxidant agent MERCK PATENT GMBH 2012-11-21 CN disclosed
CN-101437579-A Antioxidant agent MERCK PATENT GMBH (DE) 2009-05-20 CN disclosed
CN-1726903-A Nano pear cream XIAOJIE FANG (US) 2006-02-01 CN disclosed
EP-1549600-A1 KETONES AstraZeneca AB (SE) 2005-07-06 EP disclosed
WO-2004011410-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2004-02-05 WO disclosed
US-4163746-A ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1979-08-07 US disclosed