Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202473 | 0.85 | POLB (0.61) | LMNAL3MBTL1MAPK1HPGDKMT2A | |
| SCHEMBL11568628 | 0.85 | KAT6A (0.47) | LMNAL3MBTL1HPGDKMT2AMEN1 | |
| SCHEMBL21437911 | 0.85 | POLB (0.51) | L3MBTL1HPGDKMT2AMEN1MAPT | |
| SCHEMBL11559415 | 0.84 | GAA (0.54) | LMNAL3MBTL1MAPK1HPGDKMT2A | |
| SCHEMBL11566344 | 0.83 | KMT2A (0.45) | LMNAL3MBTL1MAPK1HPGDKMT2A | |
| SCHEMBL11566907 | 0.83 | MAPK1 (0.51) | L3MBTL1MAPK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7533334 | 0.80 | ALDH1A1 (0.54) | MAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4474958 | 0.78 | LTA4H (0.52) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL21437479 | 0.78 | EGFR (0.48) | L3MBTL1HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL22616541 | 0.77 | RAB9A (0.57) | LMNAL3MBTL1MAPK1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163746-A | ANABOLIC, 5-METHYL-7-ALKOXYISOFLAVONES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-08-07 | — | — | US | disclosed |