Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940302 | 0.91 | KMT2A (0.59) | ALOX5OR51E2KMT2AMEN1CA12 | |
| SCHEMBL21494459 | 0.84 | PDE4D (0.59) | ALOX5OR51E2KMT2AMEN1PDE4D | |
| Dihydroferulic Acid Methyl Ester SCHEMBL490876 | 0.81 | ALOX5 (0.77) | ALOX5OR51E2ALDH1A1 | |
| SCHEMBL28287006 | 0.81 | CYP19A1 (0.65) | ALOX5OR51E2KMT2AMEN1 | |
| SCHEMBL18744079 | 0.81 | ALOX5 (0.55) | ALOX5OR51E2KMT2AMEN1CA12 | |
| Phenyl Propionic Acid SCHEMBL28541899 | 0.80 | KMT2A (0.63) | ALOX5KMT2AMEN1ALDH1A1 | |
| SCHEMBL7283109 | 0.80 | ALDH1A1 (0.57) | ALOX5OR51E2KMT2AMEN1CA12 | |
| SCHEMBL16294204 | 0.80 | ALOX5 (0.54) | ALOX5OR51E2KMT2AMEN1CA12 | |
| SCHEMBL584916 | 0.80 | HTT (0.52) | ALOX5OR51E2ALDH1A1 | |
| SCHEMBL3686214 | 0.80 | HDAC1 (0.51) | ALOX5OR51E2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585371-B1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INTERNAT H (US) | 2002-04-17 | — | — | EP | disclosed |
| US-5571506-A | AROMATIC ALDEHYDE OLIGOMERS FOR TREATMENT OF CARDIOVASCULAR DISORDERS, BONE METABOLISM, ANTILIPEMIC AGENTS AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0585371-A4 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE POULENC RORER INT (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0585371-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020350-A1 | AROMATIC OLIGOMERIC COMPOUNDS USEFUL AS MIMICS OF BIOACTIVE MACROMOLECULES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | disclosed |