Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395175 | 0.89 | MAPT (0.37) | MAPTGAAALDH1A1TDP1CYP3A4 | |
| Sulfuric Acid SCHEMBL9511477 | 0.81 | ALDH1A1 (0.35) | NT5EMAPTKDM4EGAAALDH1A1 | |
| Sulfuric Acid SCHEMBL8723533 | 0.73 | MAPT (0.36) | NT5EMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL8517257 | 0.70 | MAPT (0.32) | MAPTGAAALDH1A1TDP1CYP3A4 | |
| SCHEMBL4625085 | 0.70 | NQO1 (0.33) | MAPTGAAALDH1A1 | |
| Sulfuric Acid SCHEMBL8723114 | 0.70 | CA5A (0.32) | — | |
| Sulfuric Acid SCHEMBL2398134 | 0.69 | NT5E (0.34) | NT5EMAPTKDM4EGAAALDH1A1 | |
| Sulfuric Acid SCHEMBL10622885 | 0.69 | CA5A (0.30) | — | |
| Sulfuric Acid SCHEMBL11468643 | 0.68 | CA12 (0.38) | NT5EMAPTKDM4EGAAALDH1A1 | |
| Sulfuric Acid SCHEMBL20815930 | 0.67 | PDPK1 (0.34) | NT5EMAPTKDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1197203-A1 | Hair dye composition | GOLDWELL GmbH (DE) | 2002-04-17 | — | — | EP | disclosed |
| EP-1103248-B1 | Hair dyeing composition comprising N-ethyl-N-isopropyl-p-phenylenediamine | GOLDWELL GMBH (DE) | 2001-08-22 | — | — | EP | disclosed |
| EP-1103248-A1 | Hair dyeing composition comprising N-ethyl-N-isopropyl-p-phenylenediamine | GOLDWELL GmbH (DE) | 2001-05-30 | — | — | EP | disclosed |