Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719360 | 0.87 | MGAM (0.48) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL7527670 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL8837227 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL7523302 | 0.77 | KDM4E (0.43) | ALDH1A1MAPTKDM4ETHRBALOX15 | |
| SCHEMBL1332017 | 0.74 | LMNA (0.53) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL1332187 | 0.74 | LMNA (0.53) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL1331748 | 0.74 | LMNA (0.53) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL1330728 | 0.74 | LMNA (0.53) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL81193 | 0.74 | LMNA (0.53) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL6001470 | 0.73 | CAD (0.44) | ALDH1A1LMNAHSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1990015069-A2 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |