Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533911 | 0.73 | FKBP1A (0.47) | FKBP1AFKBP4FKBP5ABCC1ABCG2 | |
| SCHEMBL1233420 | 0.69 | FKBP1A (0.74) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL1233422 | 0.69 | FKBP1A (0.74) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7533919 | 0.67 | FKBP1A (0.48) | FKBP1AFKBP4FKBP5ABCC1ABCG2 | |
| SCHEMBL7473829 | 0.67 | FKBP1A (0.48) | FKBP1AFKBP4FKBP5ABCC1ABCG2 | |
| SCHEMBL7533920 | 0.67 | FKBP1A (0.48) | FKBP1AFKBP4FKBP5ABCC1ABCG2 | |
| SCHEMBL21471518 | 0.67 | FKBP1A (0.67) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL1233000 | 0.67 | FKBP1A (0.73) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7155851 | 0.66 | FKBP1A (0.80) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL5966161 | 0.66 | FKBP1A (0.80) | FKBP1AFKBP4FKBP5ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |