Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811929 | 0.89 | KDM1A (0.44) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL7940907 | 0.89 | AHR (0.44) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL29362089 | 0.89 | KDM1A (0.44) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL23351729 | 0.88 | KDM1A (0.48) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL23557091 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL6951667 | 0.78 | RAPGEF4 (0.38) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL23539570 | 0.78 | KDM1A (0.48) | ALDH1A1TDP1KDM1AMAPTKDM1B | |
| SCHEMBL8492289 | 0.78 | GAA (0.50) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL18129369 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TDP1CYP3A4KDM1AMAPT | |
| SCHEMBL12378577 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TDP1KDM1AMAPTKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598338-B1 | Process for the preparation of 1,3 - difluorbenzene | HOECHST AG (DE) | 1997-03-12 | — | — | EP | claimed |
| US-5504264-A | REDUCTIVE DEHALOGENATION OF A 1,3-DIFLUOROCHLORO- OR BROMOBENZENE USING HYDROGEN, A PALLADIUM SUPPORTED CATALYST AND AN AMINE ACID ACCEPTOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | claimed |
| EP-0562435-B1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AG (DE) | 1995-06-07 | — | — | EP | claimed |
| EP-0598338-A1 | Process for the preparation of 1,3 - difluorbenzene | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-25 | — | — | EP | claimed |
| US-5294742-A | Process for preparing 3,5-difluoroaniline | HOECHST ATKIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | claimed |
| EP-0562435-A1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | claimed |
| EP-4719022-A2 | NITROGEN-CONTAINING HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC Ireland Limited (IE) | 2026-04-01 | — | — | EP | disclosed |
| US-20250185505-A1 | NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2025-06-05 | — | — | US | disclosed |
| US-20250171684-A1 | AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2025-05-29 | — | — | US | disclosed |
| WO-2023161168-A1 | AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023161167-A1 | NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-08-31 | — | — | WO | disclosed |
| WO-2016124139-A1 | HETEROCYCLIC-SUBSTITUTED N-SULFONYLBENZAMIDE DERIVATIVES, PREPARATION METHOD FOR DERIVATIVES, AND PHARMACEUTICAL USE OF DERIVATIVES | 上海海雁医药科技有限公司 | 2016-08-11 | — | — | WO | disclosed |
| EP-0878461-B1 | Process for the preparation of 3,5-difluoroaniline | CLARIANT GMBH (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-5504264-A | REDUCTIVE DEHALOGENATION OF A 1,3-DIFLUOROCHLORO- OR BROMOBENZENE USING HYDROGEN, A PALLADIUM SUPPORTED CATALYST AND AN AMINE ACID ACCEPTOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0562435-B1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AG (DE) | 1995-06-07 | — | — | EP | disclosed |
| EP-0598338-A1 | Process for the preparation of 1,3 - difluorbenzene | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-25 | — | — | EP | disclosed |
| US-5294742-A | Process for preparing 3,5-difluoroaniline | HOECHST ATKIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| US-5294742-A | Process for preparing 3,5-difluoroaniline | HOECHST ATKIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| EP-0562435-A1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0562435-A1 | Process for the preparation of 3,5-difluoroaniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171684-A1 | AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | AHR, PAH, DDT | ALDH1A1 1102/4885TDP1 2684/4885CYP3A4 226/4885 |
| US-20250185505-A1 | NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES | NES, NUDC, HCN2 | ALDH1A1 2145/4885TDP1 2341/4885CYP3A4 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.