Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23351729 | 0.93 | KDM1A (0.48) | AHRKDM1AMAPK1KDM1BALDH1A1 | |
| SCHEMBL7534006 | 0.89 | ALDH1A1 (0.46) | AHRKDM1AMAPK1KDM1BALDH1A1 | |
| SCHEMBL811929 | 0.86 | KDM1A (0.44) | KDM1AKDM1BALDH1A1TDP1HPGD | |
| SCHEMBL29362089 | 0.86 | KDM1A (0.44) | KDM1AKDM1BALDH1A1TDP1HPGD | |
| SCHEMBL9182733 | 0.85 | AHR (0.41) | AHRKDM1AMAPK1KDM1BALDH1A1 | |
| SCHEMBL29638155 | 0.85 | AHR (0.41) | AHRKDM1AMAPK1KDM1BALDH1A1 | |
| Carbamic Acid SCHEMBL11793936 | 0.82 | ALPL (0.42) | KDM1AKDM1BHPGDTSHRSLC2A1 | |
| SCHEMBL27192516 | 0.78 | KDM1A (0.40) | KDM1AKDM1BALDH1A1TDP1MAPT | |
| SCHEMBL1397113 | 0.76 | KDM1A (0.44) | AHRKDM1AKDM1BALDH1A1TDP1 | |
| SCHEMBL11714444 | 0.76 | HSD17B10 (0.60) | MAPK1ALDH1A1TDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| US-5723613-A | Process for the free-radical chlorination or bromination of methyl aromatic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0537540-B1 | Process for the radical chlorination or bromination of methyl substituted aromatics | BAYER AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0163230-B2 | Process for producing aromatic chlorine compounds | ASAHI GLASS CO LTD (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0537540-A1 | Process for the radical chlorination or bromination of methyl substituted aromatics | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0163230-B1 | PROCESS FOR PRODUCING AROMATIC CHLORINE COMPOUNDS | ASAHI GLASS COMPANY LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |