SCHEMBL7534100

SCHEMBL7534100

COC1=CC(c2ccccc2)C=CC1(O)CC=C(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK2 O43353 1/20 0.31
ABCB11 O95342 1/20 0.30
LMNA P02545 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4680499 0.70 KDM1A (0.34)
SCHEMBL9466795 0.63 CHRNA7 (0.34)
SCHEMBL4331945 0.62 ADORA3 (0.32)
SCHEMBL8970777 0.61 MAPT (0.43)
SCHEMBL5071461 0.60 HTR2A (0.33)
SCHEMBL5152968 0.60 CHRNA7 (0.30)
SCHEMBL7199456 0.60 CHRNA7 (0.41)
Ether SCHEMBL7110170 0.59 TSHR (0.35) LMNA
SCHEMBL8458791 0.59 KDM1A (0.32)
SCHEMBL222998 0.59 CHRNA7 (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002014252-A2 COMPOSITIONS CONTAINING HYPOGLYCEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed