Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 16/20 | 0.45 |
| ▸ | NOS3 | P29474 | 12/20 | 0.44 |
| ▸ | NOS2 | P35228 | 8/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534301 | 0.79 | NOS1 (0.47) | NOS1NOS3NOS2MCHR1 | |
| SCHEMBL6700027 | 0.73 | NOS1 (0.50) | NOS1NOS3NOS2 | |
| SCHEMBL6700692 | 0.71 | NOS1 (0.52) | NOS1NOS3NOS2 | |
| SCHEMBL27517402 | 0.71 | NOS3 (0.39) | NOS1NOS3NOS2 | |
| SCHEMBL6698874 | 0.70 | NOS1 (0.43) | NOS1NOS3NOS2MCHR1 | |
| SCHEMBL6700030 | 0.70 | NOS1 (0.58) | NOS1NOS3NOS2 | |
| SCHEMBL218971 | 0.67 | MCHR1 (0.45) | NOS1NOS3NOS2TLR8MCHR1 | |
| SCHEMBL220790 | 0.66 | NOS1 (0.58) | NOS1NOS3NOS2 | |
| SCHEMBL221742 | 0.66 | NOS1 (0.51) | NOS1NOS3NOS2TLR8MCHR1 | |
| SCHEMBL21223572 | 0.65 | TLR8 (0.50) | TLR8CHRNA7MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007512-B1 | BRANCHED ALKOXY-SUBSITUTED 2-AMINOPYRIDINES AS NOS INHIBITORS | PFIZER PROD INC (US) | 2002-04-03 | — | — | EP | claimed |