Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 16/20 | 0.47 |
| ▸ | NOS3 | P29474 | 12/20 | 0.47 |
| ▸ | NOS2 | P35228 | 9/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534135 | 0.79 | NOS1 (0.45) | NOS1NOS3NOS2MCHR1 | |
| SCHEMBL6700153 | 0.74 | NOS1 (0.48) | NOS1NOS3NOS2PDE4A | |
| SCHEMBL6699927 | 0.74 | NOS1 (0.47) | NOS1NOS3NOS2PDE4A | |
| SCHEMBL6699975 | 0.73 | NOS3 (0.46) | NOS1NOS3NOS2 | |
| SCHEMBL6703557 | 0.72 | NOS1 (0.48) | NOS1NOS3NOS2MCHR1 | |
| SCHEMBL6702828 | 0.72 | NOS3 (0.45) | NOS1NOS3NOS2 | |
| SCHEMBL6697919 | 0.72 | NOS3 (0.45) | NOS1NOS3NOS2 | |
| SCHEMBL6703574 | 0.70 | NOS1 (0.48) | NOS1NOS3NOS2 | |
| SCHEMBL6702757 | 0.70 | NOS1 (0.49) | NOS1NOS3NOS2MCHR1 | |
| SCHEMBL6703553 | 0.69 | NOS3 (0.46) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007512-B1 | BRANCHED ALKOXY-SUBSITUTED 2-AMINOPYRIDINES AS NOS INHIBITORS | PFIZER PROD INC (US) | 2002-04-03 | — | — | EP | claimed |