Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | GHSR | Q92847 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | MMP3 | P08254 | 4/20 | 0.56 |
| ▸ | MMP7 | P09237 | 4/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534274 | 1.00 | ALDH1A1 (0.62) | ALDH1A1HTTGHSRMMP1MMP3 | |
| SCHEMBL7533200 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HTTMMP1MMP3MMP7 | |
| SCHEMBL7533195 | 0.90 | ALDH1A1 (0.64) | ALDH1A1HTTMMP1MMP3MMP7 | |
| SCHEMBL2707039 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HTTGHSRMMP13FKBP1A | |
| SCHEMBL30119469 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HTTGHSRMMP13FKBP1A | |
| SCHEMBL2707034 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HTTGHSRMMP13FKBP1A | |
| SCHEMBL7532596 | 0.88 | MMP1 (0.73) | GHSRMMP1MMP3MMP7MMP13 | |
| SCHEMBL7532601 | 0.88 | MMP1 (0.73) | GHSRMMP1MMP3MMP7MMP13 | |
| SCHEMBL7923021 | 0.87 | MMP1 (0.75) | GHSRMMP1MMP3MMP7MMP13 | |
| SCHEMBL7923015 | 0.87 | MMP1 (0.75) | GHSRMMP1MMP3MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1992-H1 | INHIBITION OF METALLOPROTEINASES AND TUMOR NECROSIS FACTOR CONVERTASE WHICH DEGRADE PROTEIN COMPONENTS OF EXTRACELLULAR MATRIX | AGOURON PHARMACEUTICALS, INC. | 2001-09-04 | — | — | US | disclosed |
| WO-1998050348-A1 | METALLOPROTEINASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PHARMACEUTICAL USES | AGOURON PHARMACEUTICALS, INC. (US) | 1998-11-12 | — | — | WO | disclosed |