Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.58 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.50 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.49 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521259 | 1.00 | RPS6KA3 (0.58) | RPS6KA3SENP2SENP1SENP3MEN1 | |
| SCHEMBL12486710 | 0.78 | RPS6KA3 (0.67) | RPS6KA3MEN1ALDH1A1MAPTTHRB | |
| SCHEMBL12486707 | 0.78 | RPS6KA3 (0.67) | RPS6KA3MEN1ALDH1A1MAPTTHRB | |
| SCHEMBL15293568 | 0.78 | ENPP2 (0.54) | RPS6KA3SENP2SENP1SENP3MEN1 | |
| SCHEMBL9613349 | 0.76 | ENPP2 (0.54) | SENP2SENP1SENP3MEN1ALDH1A1 | |
| SCHEMBL11128580 | 0.75 | ENPP2 (0.54) | RPS6KA3SENP2SENP1SENP3MEN1 | |
| SCHEMBL3917038 | 0.75 | ATIC (0.58) | RPS6KA3SENP2SENP1SENP3MEN1 | |
| SCHEMBL944050 | 0.75 | ENPP2 (0.54) | RPS6KA3SENP2SENP1SENP3MEN1 | |
| SCHEMBL4338493 | 0.75 | PHLPP2 (0.54) | RPS6KA3SENP2SENP1SENP3MEN1 | |
| SCHEMBL4338500 | 0.75 | PHLPP2 (0.54) | RPS6KA3SENP2SENP1SENP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020055602-A1 | Aromatic polyisocyanates blocked by pyrazole or pyrazole derivatives and the preparation and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-09 | — | — | US | disclosed |
| US-6022449-A | HIGHER RETENTION BUT ALSO TO IMPROVED DRY AND WET STRENGTH AND SIZING. | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| US-5166232-A | CELLULOSE/PLASTIC BLENDS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE | WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| US-4544683-A | GYPSUM-POLYURETHANE OR POLYURETHANE-POLYUREA | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |