Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457464 | 1.00 | ACHE (0.57) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7804987 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7803301 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7804961 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7797292 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL9061677 | 0.90 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL16053917 | 0.90 | ACHE (0.56) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL16054345 | 0.90 | ACHE (0.56) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL17852152 | 0.88 | ACHE (0.54) | ACHEDPP7 | |
| SCHEMBL20192789 | 0.87 | GSR (0.56) | ACHEDPP7GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028814-A2 | NMDA RECEPTOR CHANNEL BLOCKER WITH NEUROPROTECTIVE ACTIVITY | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |