SCHEMBL17852152

SCHEMBL17852152

CCCOC(=O)NCCC[C@H](N)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.54
OTC P00480 1/20 0.48
DPP7 Q9UHL4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23608137 0.95 ACHE (0.53) ACHEDPP7
SCHEMBL23385458 0.95 ACHE (0.53) ACHEDPP7
SCHEMBL23607693 0.95 ACHE (0.53) ACHEDPP7
SCHEMBL9061677 0.90 ACHE (0.64) ACHE
SCHEMBL457464 0.88 ACHE (0.57) ACHEDPP7
SCHEMBL7534573 0.88 ACHE (0.57) ACHEDPP7
SCHEMBL20192790 0.86 GSR (0.50) ACHEOTC
SCHEMBL7803301 0.85 ACHE (0.62) ACHEDPP7
SCHEMBL7804987 0.85 ACHE (0.62) ACHEDPP7
SCHEMBL7797292 0.85 ACHE (0.62) ACHEDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981908-B2 Amino acid derivatives MEDIMMUNE LIMITED (GB) 2018-05-29 US disclosed
US-20160176811-A1 Amino Acid Derivatives ALLOZYNE, INC. 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160176811-A1 Amino Acid Derivatives BCAT2, BCAT1, DAO ACHE 4790/4885OTC 2283/4885DPP7 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.