Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534573 | 1.00 | ACHE (0.57) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7804987 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7803301 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7804961 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL7797292 | 0.94 | ACHE (0.62) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL9061677 | 0.90 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL16053917 | 0.90 | ACHE (0.56) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL16054345 | 0.90 | ACHE (0.56) | ACHEDPP7EPHX2GNAI3GNAO1 | |
| SCHEMBL17852152 | 0.88 | ACHE (0.54) | ACHEDPP7 | |
| SCHEMBL20192789 | 0.87 | GSR (0.56) | ACHEDPP7GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065272-A1 | Synthesis of Site Specifically-Linked Ubiquitin | MEDICAL RESEARCH COUNCIL (GB) | 2013-03-14 | — | — | US | claimed |
| EP-2046733-A1 | PROCESS FOR THE PREPARATION OF EPSILON-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2009-04-15 | — | — | EP | claimed |
| WO-2008014811-A1 | PROCESS FOR THE PREPARATION OF ε-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2008-02-07 | — | — | WO | claimed |
| EP-1088020-A1 | FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) | 2001-04-04 | — | — | EP | claimed |
| WO-1999064495-A1 | FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF | ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) | 1999-12-16 | — | — | WO | claimed |
| EP-4176050-A1 | PYRROLYSYL-TRNA SYNTHETASE VARIANTS AND USES THEREOF | enGenes Biotech GmbH (AT) | 2023-05-10 | — | — | EP | disclosed |
| CN-113880849-B | Chiral lysine modified zinc phthalocyanine and preparation method and application thereof | 南京师范大学 | 2022-12-16 | — | — | CN | disclosed |
| WO-2022003142-A1 | PYRROLYSYL-tRNA SYNTHETASE VARIANTS AND USES THEREOF | ENGENES BIOTECH GMBH (AT) | 2022-01-06 | — | — | WO | disclosed |
| EP-3720472-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI OF BETWEEN 5.8 AND 8.5 AND A COPOLYAMINO ACID CARRYING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS | Adocia (FR) | 2020-10-14 | — | — | EP | disclosed |
| EP-3607326-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | Revolution Medicines, Inc. (US) | 2020-02-12 | — | — | EP | disclosed |
| WO-2019110625-A1 | INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI OF BETWEEN 5.8 AND 8.5 AND A COPOLYAMINO ACID CARRYING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS | ADOCIA (FR) | 2019-06-13 | — | — | WO | disclosed |
| WO-2019010164-A1 | EVOLUTION OF TRNA SYNTHETASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |
| WO-1999002549-A1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0817796-A1 | CYCLIC PEPTIDE NUCLEI AND DERIVATIVES THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030399-A1 | CYCLIC PEPTIDE NUCLEI AND DERIVATIVES THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |
| EP-0722456-A1 | ANTIFUNGAL COMPOSITIONS | BTG INTERNATIONAL LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |
| EP-0672130-A1 | PEPTIDE CORRESPONDING TO CD44 EXON 6, ANTIBODIES SPECIFIC FOR SAID PEPTIDE AND USE OF THESE ANTIBODIES FOR DIAGNOSIS OF TUMORS | ISIS INNOVATION LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995009867-A1 | ANTIFUNGAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-04-13 | — | — | WO | disclosed |
| WO-1994012631-A1 | PEPTIDE CORRESPONDING TO CD44 EXON 6, ANTIBODIES SPECIFIC FOR SAID PEPTIDE AND USE OF THESE ANTIBODIES FOR DIAGNOSIS OF TUMORS | ISIS INNOVATION LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065272-A1 | Synthesis of Site Specifically-Linked Ubiquitin | SUMO2, STUB1, UBE3C | ACHE 3258/4885DPP7 530/4885EPHX2 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.