Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.51 |
| ▸ | NPY4R | P50391 | 12/20 | 0.51 |
| ▸ | NPY1R | P25929 | 8/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.51 |
| ▸ | NPY2R | P49146 | 5/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.48 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2921577 | 0.95 | MMP2 (0.55) | BMP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL2922115 | 0.93 | NPY4R (0.49) | BMP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7116210 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL2928771 | 0.90 | F2 (0.53) | BMP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7125358 | 0.88 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RF2 | |
| SCHEMBL4642667 | 0.87 | NPY5R (0.52) | NPY4RNPY1RNPY5RNPY2RF2 | |
| SCHEMBL2928319 | 0.86 | MMP2 (0.53) | BMP1MMP2MMP9 | |
| SCHEMBL2922269 | 0.84 | NPY4R (0.47) | BMP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7116399 | 0.84 | NPY4R (0.48) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL7111184 | 0.84 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024192-A1 | DIPEPTIDE LIGANDS OF THE NPFF RECEPTOR FOR TREATING PAIN AND HYPERALGESIA | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2002-03-28 | — | — | WO | disclosed |