SCHEMBL2928771

SCHEMBL2928771

N=C(N)NCCC[C@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.53
BMP1 P13497 2/20 0.49
PLG P00747 3/20 0.48
HPN P05981 2/20 0.48
ST14 Q9Y5Y6 2/20 0.48
HGFAC Q04756 1/20 0.47
NPY5R Q15761 4/20 0.47
NPY4R P50391 4/20 0.47
F10 P00742 3/20 0.47
NPY1R P25929 3/20 0.47
NPY2R P49146 3/20 0.47
PLAU P00749 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7123004 0.91 NPY4R (0.46) F2PLGHPNST14HGFAC
SCHEMBL7534730 0.90 BMP1 (0.51) F2BMP1NPY5RNPY4RNPY1R
SCHEMBL2922115 0.89 NPY4R (0.49) F2BMP1NPY5RNPY4RNPY1R
SCHEMBL2921577 0.89 MMP2 (0.55) F2BMP1NPY5RNPY4RNPY1R
SCHEMBL7752667 0.85 SLC1A3 (0.52) F2PLGHPNST14HGFAC
SCHEMBL4642667 0.85 NPY5R (0.52) F2PLGNPY5RNPY4RF10
SCHEMBL7125358 0.82 NPY4R (0.51) F2PLGNPY5RNPY4RF10
SCHEMBL2927549 0.82 F10 (0.54) F2PLGHPNST14HGFAC
SCHEMBL5780617 0.81 F2 (0.61) F2PLGNPY5RF10PLAU
SCHEMBL6551485 0.81 MC4R (0.57) NPY5RNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675824-B1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS WURSTER SIEGFRIED (FI) 2010-09-29 EP disclosed
US-20030144310-A1 Molecules specific for NPFF receptors and uses thereof H. LUNDBECK A/S (DK) 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144310-A1 Molecules specific for NPFF receptors and uses thereof NPFFR1, NPFFR2, NPBWR1 F2 3607/4885BMP1 1790/4885PLG 4602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.