Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.58 |
| ▸ | MMP9 | P14780 | 7/20 | 0.58 |
| ▸ | MMP8 | P22894 | 6/20 | 0.58 |
| ▸ | MMP1 | P03956 | 13/20 | 0.58 |
| ▸ | MMP3 | P08254 | 12/20 | 0.58 |
| ▸ | PDE4A | P27815 | 6/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.57 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BMP1 | P13497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077710 | 0.91 | MMP2 (0.70) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7422537 | 0.89 | MMP2 (0.56) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7431052 | 0.88 | MMP2 (0.58) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7423442 | 0.86 | MMP1 (0.53) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL1858392 | 0.83 | ALDH1A1 (0.57) | MMP2MMP1MMP3PDE4APDE4B | |
| SCHEMBL7083877 | 0.81 | MMP2 (0.57) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7432957 | 0.81 | MMP2 (0.53) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL6575906 | 0.80 | MMP2 (0.47) | MMP2MMP9MMP8MMP1MMP3 | |
| Anisole SCHEMBL28943732 | 0.80 | MMP1 (0.48) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL1855703 | 0.80 | ALDH1A1 (0.54) | MMP2MMP1MMP3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051395-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2000-11-15 | — | — | EP | disclosed |
| US-6100266-A | Hydroxamic and carboxylic acid derivatives | DARWIN DISCOVERY LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
| WO-1999038843-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |