Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | CA1 | P00915 | 5/20 | 0.51 |
| ▸ | CA9 | Q16790 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526892 | 0.84 | GPR35 (0.64) | GPR35KMT2AMEN1CA2CA1 | |
| SCHEMBL27558539 | 0.82 | GPR35 (0.62) | GPR35KMT2AMEN1CA2CA1 | |
| SCHEMBL1121443 | 0.82 | GPR35 (0.62) | GPR35KMT2AMEN1CA2CA1 | |
| SCHEMBL370668 | 0.81 | KMT2A (0.70) | KMT2AMEN1CA2CA1CA9 | |
| SCHEMBL4158554 | 0.81 | KMT2A (0.70) | KMT2AMEN1CA2CA1CA9 | |
| SCHEMBL7531976 | 0.80 | KMT2A (0.53) | GPR35KMT2AMEN1CA2CA1 | |
| SCHEMBL414795 | 0.80 | GPR35 (0.56) | GPR35KMT2AMEN1CA2CA1 | |
| SCHEMBL30075050 | 0.80 | KMT2A (0.53) | GPR35KMT2AMEN1CA2CA1 | |
| Hydrochloric Acid SCHEMBL28910568 | 0.79 | KMT2A (0.68) | KMT2AMEN1CA2CA1CA9 | |
| SCHEMBL22719534 | 0.79 | KMT2A (0.68) | KMT2AMEN1CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463993-B1 | Process for the preparation of aminoanthraquinone derivatives | CIBA SC HOLDING AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| US-5196553-A | From bromaminic acid and a benzenesulfonamide or an amide, copper/I/ catalyst formed by in situ reduction of a copper/II/ salt, less copper required | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0463993-A1 | Process for the preparation of aminoanthraquinone derivatives | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |