Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535177 | 0.89 | CHRM4 (0.39) | BRD4CHRM4KDM4ETSHRALDH1A1 | |
| SCHEMBL6173264 | 0.84 | ALDH1A1 (0.49) | CHRM4KDM4ETSHRALDH1A1MAPT | |
| SCHEMBL6173452 | 0.66 | ALDH1A1 (0.47) | KDM4ETSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL6172975 | 0.65 | ALDH1A1 (0.44) | CHRM4KDM4ETSHRALDH1A1MAPT | |
| SCHEMBL1919282 | 0.65 | ALDH1A1 (0.52) | CHRM4KDM4ETSHRALDH1A1MAPT | |
| SCHEMBL6171996 | 0.65 | ALDH1A1 (0.41) | KDM4ETSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL352276 | 0.64 | GAA (0.53) | KDM4ETSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL6173638 | 0.63 | PDE4B (0.51) | KDM4ETSHRALDH1A1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL5009791 | 0.62 | GAA (0.51) | KDM4ETSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL6171650 | 0.62 | ALOX15 (0.58) | KDM4ETSHRALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263757-A1 | BENZTHIAZOLES AS TNF AND PDE-IV INHIBITORS | Darwin Discovery Limited (GB) | 2002-12-11 | — | — | EP | claimed |
| WO-2001058897-A1 | BENZTHIAZOLES AS TNF AND PDE-IV INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-08-16 | — | — | WO | claimed |