Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535197 | 0.89 | TTR (0.40) | TTRLPAR1LPAR5MRGPRX4SRD5A2 | |
| SCHEMBL7922539 | 0.83 | TTR (0.44) | TTRHRH1LPAR1LPAR5HTR2A | |
| SCHEMBL11159132 | 0.81 | APP (0.47) | TTR | |
| SCHEMBL6908530 | 0.80 | LMNA (0.42) | TTRLPAR1LPAR5SRD5A2HTR2A | |
| SCHEMBL11141496 | 0.80 | TSHR (0.48) | TTRLPAR1LPAR5MRGPRX4 | |
| SCHEMBL10743171 | 0.80 | TTR (0.44) | TTRHRH1LPAR1LPAR5SRD5A2 | |
| SCHEMBL11313598 | 0.79 | TTR (0.39) | TTRLPAR1LPAR5MRGPRX4SRD5A2 | |
| SCHEMBL11313592 | 0.79 | TTR (0.39) | TTRLPAR1LPAR5MRGPRX4SRD5A2 | |
| Hydrochloric Acid SCHEMBL8695686 | 0.79 | IDO1 (0.47) | HRH1 | |
| SCHEMBL10740183 | 0.78 | TTR (0.47) | TTRHRH1LPAR1LPAR5HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202948-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| EP-1159241-A1 | PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-05 | — | — | EP | disclosed |
| WO-2001012578-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000029363-A1 | PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |