Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535192 | 0.89 | TTR (0.39) | TTRLPAR1LPAR5MRGPRX4SRD5A2 | |
| SCHEMBL7922539 | 0.81 | TTR (0.44) | TTRLPAR1LPAR5FFAR4 | |
| SCHEMBL11159132 | 0.79 | APP (0.47) | TTRFFAR1FFAR4 | |
| SCHEMBL11141496 | 0.78 | TSHR (0.48) | TTRLPAR1LPAR5MRGPRX4FFAR4 | |
| SCHEMBL6908530 | 0.78 | LMNA (0.42) | TTRLPAR1LPAR5LMNASRD5A2 | |
| SCHEMBL9539557 | 0.77 | TTR (0.65) | TTRLPAR1LPAR5 | |
| SCHEMBL10743171 | 0.77 | TTR (0.44) | TTRLPAR1LPAR5SRD5A2 | |
| SCHEMBL11313598 | 0.77 | TTR (0.39) | TTRLPAR1LPAR5LMNAMRGPRX4 | |
| SCHEMBL11313592 | 0.77 | TTR (0.39) | TTRLPAR1LPAR5L3MBTL1LMNA | |
| SCHEMBL11408608 | 0.77 | MEN1 (0.43) | TTRLPAR1LPAR5L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202948-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| EP-1159241-A1 | PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-05 | — | — | EP | disclosed |
| WO-2001012578-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000029363-A1 | PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |