⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767434 | 0.63 | TP53 (0.30) | — | |
| SCHEMBL16163572 | 0.57 | LMNA (0.46) | — | |
| SCHEMBL11171758 | 0.56 | LMNA (0.34) | — | |
| SCHEMBL13177602 | 0.54 | ALDH1A1 (0.42) | — | |
| SCHEMBL10984707 | 0.54 | ALDH1A1 (0.39) | — | |
| SCHEMBL633287 | 0.54 | LMNA (0.70) | — | |
| SCHEMBL7511548 | 0.54 | LMNA (0.54) | — | |
| SCHEMBL5415660 | 0.53 | LMNA (0.48) | — | |
| SCHEMBL1819894 | 0.53 | ALDH1A1 (0.67) | — | |
| SCHEMBL2720684 | 0.52 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104429-B1 | ANSA GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES | DOW CHEMICAL CO (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-1104429-A1 | ANSA GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-06 | — | — | EP | disclosed |
| US-6140521-A | CONTACTING A CHARGE-NEUTRAL GROUP IV METAL COORDINATION COMPLEX HAVING AT LEAST TWO LEWIS BASIC GROUPS WITH A CHARGE-NEUTRAL ALUMINUM COORDINATION COMPLEXES HAVING LEWIS ACIDIC ALUMINUM ATOMS; OLEFIN POLYMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| WO-2000009523-A1 | ANSA-GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-02-24 | — | — | WO | disclosed |