SCHEMBL7767434

SCHEMBL7767434

CCCC(=O)N([Ti])[Si](C)(C)C1=C(C)C(C)=C(C)C1C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535515 0.63
SCHEMBL16163572 0.61 LMNA (0.46) TP53
SCHEMBL633287 0.58 LMNA (0.70) TP53
Hydrochloric Acid SCHEMBL5790083 0.58 TP53 (0.33) TP53
SCHEMBL7511548 0.57 LMNA (0.54) TP53
SCHEMBL1819894 0.57 ALDH1A1 (0.67) TP53
SCHEMBL8162945 0.56
SCHEMBL2720684 0.56 LMNA (0.41) TP53
SCHEMBL9306530 0.55 ALDH1A1 (0.64) TP53
SCHEMBL10984707 0.55 ALDH1A1 (0.39) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1104429-A1 ANSA GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-06-06 EP disclosed
WO-2000009523-A1 ANSA-GROUP-4-METAL BIS (.MU.-SUBSTITUTED) ALUMINUM COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-02-24 WO disclosed