SCHEMBL7535537

SCHEMBL7535537

O=S(=O)(Oc1ccccc1)c1ccc(O)c2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.58
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
GAA P10253 3/20 0.47
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
IDO1 P14902 2/20 0.45
CDK2 P24941 1/20 0.44
HKDC1 Q2TB90 2/20 0.43
TNNI3 P19429 1/20 0.43
TNNT2 P45379 1/20 0.43
TNNC1 P63316 1/20 0.43
LMNA P02545 2/20 0.41
EP300 Q09472 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11600779 0.92 MEN1 (0.56) LDHAMEN1KMT2AGAAESR1
SCHEMBL10879777 0.87 LDHA (0.51) LDHAMEN1KMT2AGAAESR1
SCHEMBL10879314 0.85 CA1 (0.51) LDHAMEN1KMT2AGAAESR1
SCHEMBL10875810 0.84 LDHA (0.47) LDHAMEN1KMT2AGAAESR1
SCHEMBL7542443 0.80 NR4A1 (0.44) LDHAMEN1KMT2ACA1CA2
SCHEMBL6357382 0.78 CA1 (0.52) MEN1KMT2AGAAESR1ESR2
SCHEMBL8475995 0.78 CA1 (0.44) LDHAMEN1KMT2AGAAESR1
SCHEMBL10881406 0.78 KMT2A (0.59) LDHAMEN1KMT2AGAAESR1
SCHEMBL7535587 0.78 ESR1 (0.52) LDHAMEN1KMT2AGAAESR1
SCHEMBL10877069 0.78 MEN1 (0.57) LDHAMEN1KMT2AGAAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
US-4583104-A Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 LDHA 1723/4885MEN1 3828/4885KMT2A 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.