SCHEMBL7536

SCHEMBL7536

BrCc1ccc(Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5389732 0.97 ALDH1A1 (0.50)
Iodomethane SCHEMBL8216911 0.91 ALDH1A1 (0.46)
SCHEMBL3362246 0.91 ALDH1A1 (0.50)
SCHEMBL131361 0.86 ALDH1A1 (0.67)
SCHEMBL452554 0.84 ALDH1A1 (0.40)
SCHEMBL6764664 0.84 ALDH1A1 (0.47)
SCHEMBL14948455 0.84 ALDH1A1 (0.41)
SCHEMBL3098973 0.84 ALDH1A1 (0.40)
SCHEMBL6764667 0.84 ALDH1A1 (0.47)
SCHEMBL7995493 0.81 LMNA (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6489 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
CN-115850002-B Method for hydrodehalogenating halogenated alkane 中国科学院兰州化学物理研究所 2025-05-23 CN claimed
US-12304917-B1 Pleuromutilin derivative containing a thiazolo[5,4-c]pyridine side chain, and a preparation method and application thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-05-20 US claimed
CN-119977877-A Small molecular compound and preparation and application thereof 上海交通大学医学院附属瑞金医院 2025-05-13 CN claimed
US-12275734-B1 Pleuromutilin onium salt derivative containing a 3H-imidazo[4,5-c]pyridine side chain, and a preparation method and application thereof SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-04-15 US claimed
CN-116375643-B Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2025-04-01 CN claimed
CN-119569808-A Method for modifying C-21 position structure of fusidic acid 浙江工业大学 2025-03-07 CN claimed
CN-119263950-A Synthesis method of 1, 2-bis (4-vinyl phenyl) ethane 上海康鹏科技股份有限公司 2025-01-07 CN claimed
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-118930512-A Kernel molecule capable of realizing three-arm star-shaped polymer molecule deformation, and preparation method and application thereof 复旦大学 2024-11-12 CN claimed
US-6005105-A Process for producing imidazole derivative PHARMACIA & UPJOHN COMPANY (US) 1999-12-21 US claimed
US-5837868-A REACTION OF DIHYDROXY OLEFINS IN A MULTISTAGE PROCESS ARYL METHYLAMINE TO FORM PYRROLIDINE INTERMEDIATE ABBOTT LABORATORIES (US) 1998-11-17 US claimed
US-5759734-A Method of generating simulated photographic-quality images on luminescent melt-formed backing substrates XEROX CORPORATION (US) 1998-06-02 US claimed
WO-1998022437-A1 PROCESS FOR PREPARATION OF CHIRAL 3-AMINOPYRROLIDINE AND ANALOGOUS BICYCLIC COMPOUNDS ABBOTT LABORATORIES (US) 1998-05-28 WO claimed
US-5703244-A CYCLIZATION OF DIHYDROXY OLEFINS WITH TARTRATE ESTER IN PRESENCE OF TITANIUM ISOPROPOXIDE AND TERT-BUTYL HYDROPEROXIDE ABBOTT LABORATORIES (US) 1997-12-30 US claimed
US-5312920-A Process for preparing 4-pyrimidinones SYNTHELABO (FR) 1994-05-17 US claimed
EP-0561664-A1 Process for the preparation of 4-pyrimidines SYNTHELABO (FR) 1993-09-22 EP claimed
US-4841009-A Substantially linear monomeric composition and liquid crystal polymeric compositions derived therefrom AMOCO CORPORATION (US) 1989-06-20 US claimed
US-4495353-A ETHERIFICATION OF A HALOAROMTIC COMPOUND STERLING DRUG INC. (US) 1985-01-22 US claimed
US-4248779-A REACTING CARBONYL SULFIDE WITH A SECONDARY AMINE AND REACTING THE AMINE SALT WITH A HALOHYDROCARBON IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1981-02-03 US claimed