SCHEMBL6764667

SCHEMBL6764667

BrCc1ccc(C=Cc2ccc(Br)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CYP2C19 P33261 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6764664 1.00 ALDH1A1 (0.47) ALDH1A1CYP2C19KDM4EHPGDRAB9A
SCHEMBL9004476 0.90 TRPA1 (0.48) ALDH1A1CYP2C19KDM4EHPGDRAB9A
SCHEMBL9004477 0.90 TRPA1 (0.48) ALDH1A1CYP2C19KDM4EHPGDRAB9A
SCHEMBL7536 0.84
SCHEMBL27518670 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ETRPA1TSHRHTR2A
Phosphine SCHEMBL27726130 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ETRPA1TSHRHTR2A
SCHEMBL5389732 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ETRPA1TSHRHTR2A
Ammonia Solution, Strong SCHEMBL28228784 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ETRPA1TSHRHTR2A
Bromide SCHEMBL29227177 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ETRPA1TSHRHTR2A
Fluoride SCHEMBL29026731 0.82 ALDH1A1 (0.50) ALDH1A1KDM4ETRPA1TSHRHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746784-B2 SUBSTITUTED OR UNSUBSTITUTED CYCLOHEXYLIDENEMETHINE GROUP COMPOUNDS WITH IMPROVED HOLE INJECTION PROPERTIES SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-06-08 US disclosed
US-20020058156-A1 Substituted or unsubstituted cyclohexylidenemethine group compounds with improved hole injection properties SAMSUNG DISPLAY CO., LTD. (KR) 2002-05-16 US disclosed