Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597017 | 0.95 | MEN1 (0.53) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7607637 | 0.91 | ABCB1 (0.42) | NPC1RAB9ASMN1; SMN2ABCB1MEN1 | |
| SCHEMBL6327240 | 0.83 | MEN1 (0.70) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7033981 | 0.83 | MEN1 (0.70) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| Hydrochloric Acid SCHEMBL7027080 | 0.82 | MEN1 (0.68) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7609851 | 0.82 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7612154 | 0.82 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7536453 | 0.81 | ADRB3 (0.62) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7536027 | 0.81 | ADRB3 (0.62) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7605875 | 0.80 | ADRB1 (0.46) | NPC1RAB9ASMN1; SMN2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002036552-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-10 | — | — | WO | disclosed |