Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 17/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 17/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 16/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607637 | 0.81 | ABCB1 (0.42) | ADRB1ADRB3ADRB2NPC1RAB9A | |
| SCHEMBL7611045 | 0.81 | ADRB3 (0.54) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7536025 | 0.80 | NPC1 (0.51) | ADRB1ADRB3ADRB2NPC1RAB9A | |
| SCHEMBL7605880 | 0.77 | NPC1 (0.43) | ADRB1ADRB3ADRB2NR3C1NPC1 | |
| SCHEMBL7597017 | 0.76 | MEN1 (0.53) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7614695 | 0.75 | SMN1; SMN2 (0.42) | NR3C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7614703 | 0.75 | SMN1; SMN2 (0.41) | NR3C1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7609851 | 0.71 | NPC1 (0.39) | ADRB1ADRB2NR3C1NPC1RAB9A | |
| SCHEMBL7612154 | 0.71 | NPC1 (0.39) | ADRB1ADRB2NR3C1NPC1RAB9A | |
| SCHEMBL7608477 | 0.71 | ADRB3 (0.59) | ADRB1ADRB3ADRB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |