Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536025 | 0.91 | NPC1 (0.51) | ABCB1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7612154 | 0.89 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7609851 | 0.89 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7597017 | 0.88 | MEN1 (0.53) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7605875 | 0.81 | ADRB1 (0.46) | NPC1RAB9ASMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL7610964 | 0.81 | NPC1 (0.46) | ABCB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6322792 | 0.81 | NPC1 (0.46) | ABCB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7612353 | 0.80 | NPC1 (0.48) | ABCB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6327240 | 0.76 | MEN1 (0.70) | ABCB1MEN1OPRM1OPRD1KMT2A | |
| SCHEMBL7033981 | 0.76 | MEN1 (0.70) | ABCB1MEN1OPRM1OPRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |