Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768377 | 0.91 | SMN1; SMN2 (0.48) | KMT2AMEN1MITFCASRSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL7540439 | 0.87 | SMN1; SMN2 (0.44) | KMT2AMEN1MITFCASRSMN1; SMN2 | |
| SCHEMBL7610781 | 0.86 | ADRB2 (0.40) | CASRSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL7611728 | 0.83 | ADRB2 (0.46) | CASRSMN1; SMN2HPGDADRB2ADRB1 | |
| SCHEMBL7610419 | 0.82 | KMT2A (0.54) | KMT2AMEN1MITFCASRSMN1; SMN2 | |
| SCHEMBL7613185 | 0.82 | RAB9A (0.53) | KMT2AMEN1CASRSMN1; SMN2RAB9A | |
| SCHEMBL7612545 | 0.81 | CASR (0.46) | KMT2AMEN1CASRRAB9ANPC1 | |
| SCHEMBL7610407 | 0.80 | GLA (0.48) | KMT2AMEN1CASRSMN1; SMN2RAB9A | |
| SCHEMBL7595294 | 0.80 | CASR (0.50) | KMT2AMEN1CASRALDH1A1LMNA | |
| SCHEMBL7612159 | 0.79 | RAB9A (0.46) | KMT2AMEN1CASRSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002036552-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-10 | — | — | WO | claimed |
| WO-2002036552-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-10 | — | — | WO | disclosed |