Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768377 | 0.88 | SMN1; SMN2 (0.48) | CASRMEN1KMT2AALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL7540439 | 0.84 | SMN1; SMN2 (0.44) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7536032 | 0.80 | KMT2A (0.43) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7613185 | 0.79 | RAB9A (0.53) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7612545 | 0.78 | CASR (0.46) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7610407 | 0.77 | GLA (0.48) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7612159 | 0.76 | RAB9A (0.46) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7027312 | 0.76 | MEN1 (0.65) | CASRMEN1KMT2ACYP1A2ATM | |
| SCHEMBL7022015 | 0.75 | CASR (0.53) | CASRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7610781 | 0.75 | ADRB2 (0.40) | CASRTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257528-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060786-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |