Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018738 | 0.76 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1HTTMAPT | |
| SCHEMBL1487087 | 0.74 | NOS1 (0.50) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL1135577 | 0.72 | LMNA (0.46) | KMT2AALDH1A1MEN1HTTMAPT | |
| SCHEMBL761873 | 0.71 | NOS1 (0.46) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL4102262 | 0.71 | NOS1 (0.46) | KMT2AALDH1A1MEN1HTTMAPT | |
| SCHEMBL7026517 | 0.71 | NOS1 (0.46) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL16246417 | 0.70 | ALDH1A1 (0.45) | KMT2AALDH1A1MEN1HTTMAPT | |
| SCHEMBL24399512 | 0.69 | NOS1 (0.45) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL11686744 | 0.67 | PIK3CA (0.54) | KMT2AALDH1A1MEN1HTTMAPT | |
| SCHEMBL11590741 | 0.67 | ALDH1A1 (0.85) | KMT2AALDH1A1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790057-B1 | ANTIBACTERIAL OR BACTERICIDE COMPRISING 2-AMINOTHIAZOLE DERIVATIVE AND SALTS THEREOF | HISAMITSU PHARMACEUTICAL CO (JP) | 2002-06-05 | — | — | EP | disclosed |