Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.38 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532766 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL964883 | 0.89 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL964882 | 0.89 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL27555431 | 0.88 | PTPN1 (0.43) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL7527737 | 0.84 | POLB (0.43) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL7621987 | 0.84 | POLB (0.43) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL27575302 | 0.84 | ADRB3 (0.43) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL7618225 | 0.84 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL7533145 | 0.83 | MEN1 (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL7530966 | 0.83 | MEN1 (0.46) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1360574-A | Process for preparing tricyclic amino alcohol derivatives | ASAHI CHEMICAL IND (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |