Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530966 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1PER2L3MBTL1 | |
| SCHEMBL27555232 | 0.87 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL7529497 | 0.87 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL27555237 | 0.86 | MEN1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL7617501 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1PER2L3MBTL1 | |
| SCHEMBL27575408 | 0.84 | ADRB3 (0.46) | MEN1KMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL7525839 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1PER2L3MBTL1 | |
| SCHEMBL7615025 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1PER2L3MBTL1 | |
| SCHEMBL7536141 | 0.83 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL7532766 | 0.83 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |