Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527737 | 1.00 | POLB (0.43) | POLBALDH1A1TSHRL3MBTL1GAA | |
| SCHEMBL7618225 | 0.93 | L3MBTL1 (0.40) | POLBALDH1A1L3MBTL1PTPN1PTPN2 | |
| SCHEMBL964882 | 0.86 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1PTPN1PTPN2PTPN6 | |
| SCHEMBL964883 | 0.86 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1PTPN1PTPN2PTPN6 | |
| SCHEMBL7613358 | 0.85 | ALDH1A1 (0.39) | POLBALDH1A1TSHRL3MBTL1GAA | |
| SCHEMBL7536470 | 0.85 | ALDH1A1 (0.39) | POLBALDH1A1TSHRL3MBTL1GAA | |
| SCHEMBL7617501 | 0.84 | MEN1 (0.41) | POLBALDH1A1TSHRL3MBTL1GAA | |
| SCHEMBL7525839 | 0.84 | MEN1 (0.41) | POLBALDH1A1TSHRL3MBTL1GAA | |
| SCHEMBL7532766 | 0.84 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1PTPN1PTPN2PTPN6 | |
| SCHEMBL7536141 | 0.84 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495701-B1 | THE PRESENT INVENTION IS DIRECTED TO PROCESSES FOR THE PREPARATION OF A COMPOUND USEFUL FOR TREATING DIABETES, OBESITY, HYPERLIPIDEMIA AND THE LIKE, | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1174425-A1 | NOVEL METHOD FOR MANUFACTURING TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |