⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563345 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL5926466 | 0.79 | CYP2D6 (0.34) | — | |
| SCHEMBL7538386 | 0.79 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL7563421 | 0.78 | KDM4E (0.32) | — | |
| SCHEMBL614374 | 0.77 | — | — | |
| SCHEMBL3202994 | 0.77 | — | — | |
| SCHEMBL7127138 | 0.76 | HTR1A (0.44) | — | |
| SCHEMBL7125210 | 0.75 | HRH3 (0.32) | — | |
| SCHEMBL7118543 | 0.75 | HRH3 (0.34) | — | |
| SCHEMBL7125679 | 0.75 | KMT2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-31 | — | — | US | disclosed |
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6306859-B1 | PIPERIDINE ALKYL IMIDES AS NEUROTRANSMITTERS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-23 | — | — | US | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |