Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926466 | 0.92 | CYP2D6 (0.34) | — | |
| SCHEMBL3202994 | 0.84 | — | — | |
| SCHEMBL7538386 | 0.82 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL7536359 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7563421 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL7125679 | 0.80 | KMT2A (0.46) | ALDH1A1 | |
| SCHEMBL7120323 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL7118092 | 0.79 | HTR1A (0.33) | — | |
| SCHEMBL7126559 | 0.79 | DRD2 (0.41) | — | |
| SCHEMBL7119307 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | AMERICAN HOME PRODUCTS CORPORATION | 2002-01-31 | — | — | US | disclosed |
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6306859-B1 | PIPERIDINE ALKYL IMIDES AS NEUROTRANSMITTERS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-23 | — | — | US | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013324-A1 | N-substituted imide derivatives with serotonergic activity | TPH1, HTR1A, HTR1E | ALDH1A1 630/4885ALOX15 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.