SCHEMBL7536458

SCHEMBL7536458

CC(=O)N(C(C)=O)S(=O)(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
ALDH1A1 P00352 1/20 0.61
CA12 O43570 3/20 0.57
CA2 P00918 3/20 0.57
CA9 Q16790 3/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
ABCC2 Q92887 1/20 0.57
SLC22A12 Q96S37 1/20 0.57
UGT1A7 Q9HAW7 1/20 0.57
SLC22A11 Q9NSA0 1/20 0.57
TAS2R14 Q9NYV8 8/20 0.56
CA1 P00915 2/20 0.52
CA14 Q9ULX7 2/20 0.52
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CYP2C19 P33261 1/20 0.52
CA5A P35218 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34672 0.80 ALDH1A1 (0.66) KMT2AALDH1A1CA12CA2CA9
SCHEMBL7535319 0.80 ESR1 (0.50) KMT2AALDH1A1CA12CA2CA9
SCHEMBL11406749 0.78 TSHR (0.52) KMT2AALDH1A1CA12CA2CA9
SCHEMBL34463903 0.77 TAS2R14 (0.65) KMT2AALDH1A1CA12CA2CA9
Halazone SCHEMBL29353 0.76 KMT2A (1.00) KMT2AALDH1A1CA12CA2CA9
SCHEMBL3642059 0.76 CA12 (0.59) KMT2AALDH1A1CA12CA2CA9
Etebenecid SCHEMBL1643610 0.76 SMN1; SMN2 (0.75) KMT2AALDH1A1CA12CA2CA9
SCHEMBL17908029 0.76 TAS2R14 (0.63) KMT2AALDH1A1CA12CA2CA9
SCHEMBL7545413 0.76 HTT (0.46) KMT2AALDH1A1SMN1; SMN2MEN1HTT
SCHEMBL3715136 0.74 KMT2A (0.58) KMT2AALDH1A1CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 KMT2A 3439/4885ALDH1A1 1488/4885CA12 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.