Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752097 | 0.81 | CA1 (0.36) | MAPTALDH1A1ALOX12KMT2AMEN1 | |
| SCHEMBL751642 | 0.81 | ALDH1A1 (0.42) | TDP1FFAR4MAPTALDH1A1HPGD | |
| SCHEMBL753815 | 0.75 | TSHR (0.38) | ALDH1A1KMT2AMEN1CA1CA2 | |
| SCHEMBL25910597 | 0.72 | TDP1 (0.39) | RAPGEF4TDP1TP53MAPTALDH1A1 | |
| SCHEMBL15752091 | 0.72 | TDP1 (0.35) | RAPGEF4TDP1TP53MAPTALDH1A1 | |
| SCHEMBL18242406 | 0.72 | TDP1 (0.42) | RAPGEF4TDP1TP53MAPTALDH1A1 | |
| SCHEMBL10341411 | 0.71 | TP53 (0.39) | RAPGEF4TDP1TP53FFAR4MAPT | |
| SCHEMBL751741 | 0.70 | CA1 (0.47) | TDP1ALDH1A1KMT2AMEN1CA1 | |
| SCHEMBL3815788 | 0.69 | TDP1 (0.37) | RAPGEF4TDP1TP53MAPTALDH1A1 | |
| SCHEMBL9065284 | 0.69 | TDP1 (0.44) | RAPGEF4TDP1TP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213166-B1 | Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone | THOR GMBH (DE) | 2012-03-21 | — | — | EP | claimed |