SCHEMBL753815

SCHEMBL753815

Cc1ccccc1C(I)(I)S(=O)(=O)C(I)(I)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ACHE P22303 2/20 0.38
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA12 O43570 1/20 0.32
ALDH1A1 P00352 2/20 0.32
CHRM3 P20309 1/20 0.31
CA7 P43166 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755136 0.74 L3MBTL1 (0.42) TSHRGABRA1GABRB2CYP1A2CYP3A4
SCHEMBL752097 0.72 CA1 (0.36) MEN1KMT2ACA1CA2ALDH1A1
SCHEMBL751642 0.72 ALDH1A1 (0.42) TSHRACHEMEN1CYP1A2CYP3A4
SCHEMBL13322368 0.72 TSHR (0.45) TSHRACHEGABRA1GABRB2CYP1A2
SCHEMBL758525 0.71 CA2 (0.42) TSHRMEN1CYP1A2CYP3A4KMT2A
SCHEMBL15088320 0.70 ACHE (0.43) TSHRACHEGABRA1GABRB2CYP1A2
SCHEMBL6489793 0.70 TSHR (0.43) TSHRACHEGABRA1GABRB2CYP1A2
SCHEMBL5526684 0.69 TSHR (0.47) TSHRACHEGABRA1GABRB2CYP1A2
SCHEMBL26701072 0.68 GABRA1 (0.45) TSHRACHEGABRA1GABRB2CYP3A4
SCHEMBL7112101 0.68 TSHR (0.37) TSHRACHECYP1A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1648673-B1 COMPOSITE MATERIAL HAVING THE APPEARANCE OF NATURAL STONE COSENTINO SA (ES) 2019-04-17 EP claimed
EP-2150507-B1 ANTIMICROBIAL CEMENTITIOUS COMPOSITION, METHOD AND ARTICLE MICROBAN PRODUCTS (US) 2018-04-11 EP claimed
EP-1511905-B1 ANTIMICROBIAL WALLBOARD MICROBAN PRODUCTS (US) 2013-01-09 EP claimed
EP-1549775-B1 DURABLE ANTIMICROBIAL LEATHER MICROBAN PRODUCTS (US) 2012-10-10 EP claimed
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US claimed
US-20060014810-A1 Durable antimicrobial leather MICROBAN PRODUCTS COMPANY (US) 2006-01-19 US claimed
EP-1549775-A1 DURABLE ANTIMICROBIAL LEATHER MICROBAN PRODUCTS COMPANY (US) 2005-07-06 EP claimed
WO-2004011682-A1 DURABLE ANTIMICROBIAL LEATHER MICROBAN PRODUCTS COMPANY (US) 2004-02-05 WO claimed
EP-0431752-A2 Synergistic microbicidal combinations ROHM AND HAAS COMPANY (US) 1991-06-12 EP claimed
JP-10222068-A None JP disclosed
US-8287631-B2 Compounds for preventing ghost odour THOR GMBH (DE) 2012-10-16 US disclosed
EP-1549775-B1 DURABLE ANTIMICROBIAL LEATHER MICROBAN PRODUCTS (US) 2012-10-10 EP disclosed
CN-102006916-A High viscosity fluid filtering system AMIAD FILTRATION SYSTEMS LTD 2011-04-06 CN disclosed
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone THOR GMBH (DE) 2010-07-29 US disclosed
US-20060014810-A1 Durable antimicrobial leather MICROBAN PRODUCTS COMPANY (US) 2006-01-19 US disclosed
EP-1549775-A1 DURABLE ANTIMICROBIAL LEATHER MICROBAN PRODUCTS COMPANY (US) 2005-07-06 EP disclosed
WO-2004011682-A1 DURABLE ANTIMICROBIAL LEATHER MICROBAN PRODUCTS COMPANY (US) 2004-02-05 WO disclosed
JP-H10222068-A FUNGICIDAL LABEL SEAL SONY CORP 1998-08-21 JP disclosed
EP-0431752-A2 Synergistic microbicidal combinations ROHM AND HAAS COMPANY (US) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100189811-A1 Biocide compositions comprising 3-methylisothiazolin-3-one and a haloalkyl sulphone MBTD1, MPST, B2M TSHR 4791/4885ACHE 1328/4885GABRA1 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.