Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567642 | 0.89 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7535087 | 0.88 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7533616 | 0.84 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7563215 | 0.83 | MAPT (0.54) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7533699 | 0.82 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7531699 | 0.81 | ACLY (0.61) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7539025 | 0.81 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7208737 | 0.80 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL492386 | 0.79 | SLC10A2 (0.51) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7531650 | 0.78 | ACLY (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |