Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 6/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563215 | 0.93 | MAPT (0.54) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7537098 | 0.89 | MEN1 (0.57) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7535087 | 0.84 | MEN1 (0.51) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7531331 | 0.83 | DHODH (0.55) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7533616 | 0.80 | MEN1 (0.48) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7531699 | 0.80 | ACLY (0.61) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7533699 | 0.79 | SMN1; SMN2 (0.54) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7537156 | 0.78 | EDNRA (0.51) | KMT2ALMNADHODHEDNRBEDNRA | |
| SCHEMBL7539025 | 0.78 | MEN1 (0.62) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7560628 | 0.77 | LMNA (0.63) | MEN1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |