Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | LGMN | Q99538 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716021 | 0.91 | CHKA (0.56) | CHKALGMNMAPTALDH1A1KDM4E | |
| SCHEMBL10895294 | 0.87 | SLC13A5 (0.47) | LGMNMAPTALDH1A1KDM4EHTT | |
| SCHEMBL4689823 | 0.86 | ALDH1A1 (0.52) | LGMNMAPTALDH1A1KDM4EHTT | |
| SCHEMBL20631 | 0.85 | MAPT (0.61) | LGMNMAPTALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL16209945 | 0.83 | MAPT (0.65) | LGMNMAPTALDH1A1KDM4EHTT | |
| SCHEMBL20631313 | 0.83 | LMNA (0.61) | LGMNMAPTALDH1A1KDM4EHTT | |
| SCHEMBL19822996 | 0.81 | CHKA (0.47) | CHKAMAPTALDH1A1KDM4EHTT | |
| SCHEMBL14320289 | 0.80 | PIK3R1 (0.59) | LGMNMAPTALDH1A1KDM4EHTT | |
| SCHEMBL10895297 | 0.78 | ALDH1A1 (0.45) | LGMNMAPTALDH1A1KDM4EHTT | |
| SCHEMBL4386393 | 0.78 | MAPT (0.64) | LGMNMAPTALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |