Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | LGMN | Q99538 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16209945 | 0.98 | MAPT (0.65) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL20631313 | 0.98 | LMNA (0.61) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL14320289 | 0.94 | PIK3R1 (0.59) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL4386393 | 0.92 | MAPT (0.64) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL13370287 | 0.89 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL19648927 | 0.88 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL4689823 | 0.88 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL9093746 | 0.87 | LMNA (0.71) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL22453701 | 0.85 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL7537112 | 0.85 | CHKA (0.49) | MAPTALDH1A1KDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3859 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637469-B2 | 1H-pyrazole derivative and application thereof as dual target inhibitor of Syk and VEGFR2 | OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2026-05-26 | — | — | US | claimed |
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119591550-A | Preparation method of molatinib and key intermediate | 沈阳药科大学 | 2025-03-11 | — | — | CN | claimed |
| CN-116589469-B | 1H-pyrazole derivatives as Syk and VEGFR2 double-target inhibitors and application thereof | 苏州欧康维视生物科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| EP-4112621-B1 | 1H-PYRAZOLE DERIVATIVE AND APPLICATION THEREOF AS DUAL TARGET INHIBITOR OF SYK AND VEGFR2 | OCUMENSION THERAPEUTICS SUZHOU CO LTD (CN) | 2024-07-24 | — | — | EP | claimed |
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| CN-114216976-B | Method for determining potential genotoxic impurities in rivaroxaban by high performance liquid chromatography | 江苏中邦制药有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117801813-A | Red fluorescent carbon dot and preparation method and application thereof | 山西大学 | 2024-04-02 | — | — | CN | claimed |
| CN-116768862-A | Indole pyrazole compound as well as preparation method and application thereof | 郑州大学 | 2023-09-19 | — | — | CN | claimed |
| US-20230219960-A1 | 1H-PYRAZOLE DERIVATIVE AND APPLICATION THEREOF AS DUAL TARGET INHIBITOR OF SYK AND VEGFR2 | OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2023-07-13 | — | — | US | claimed |
| US-4865618-A | New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-4865619-A | Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| EP-0295474-A1 | Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions | L'OREAL (FR) | 1988-12-21 | — | — | EP | claimed |
| EP-0294669-A1 | Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair | L'OREAL (FR) | 1988-12-14 | — | — | EP | claimed |
| US-4692166-A | OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE | L'OREAL (FR) | 1987-09-08 | — | — | US | claimed |
| US-4337061-A | NITRO DYES IN AQUEOUS SOLUTION | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-29 | — | — | US | claimed |
| US-4200432-A | HAIR DYES | L'OREAL (FR) | 1980-04-29 | — | — | US | claimed |
| US-3961879-A | P-PHENYLENEDIAMINE, HAIR | L'OREAL (FR) | 1976-06-08 | — | — | US | claimed |
| US-3948596-A | Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-04-06 | — | — | US | claimed |