Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20046666 | 0.83 | MEN1 (0.47) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL3632923 | 0.82 | MEN1 (0.43) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL1615193 | 0.81 | MEN1 (0.46) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL29535934 | 0.81 | MEN1 (0.46) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL27559489 | 0.78 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1TDP1NAPRT | |
| SCHEMBL479985 | 0.78 | KMT2A (0.47) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL1318334 | 0.78 | GRM5 (0.51) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL29948993 | 0.78 | KMT2A (0.47) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL6377192 | 0.77 | MEN1 (0.46) | MEN1KMT2ASIRT6ALDH1A1TDP1 | |
| SCHEMBL7540465 | 0.75 | KMT2A (0.37) | MEN1KMT2AALDH1A1TDP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364940-A | For treatment of sewage sludge with cultures | LONZA LTD. (CH) | 1994-11-15 | — | — | US | claimed |
| EP-0559116-A2 | Microbiological process for the hydroxylation of nitrogen containing heterocyclic carbonic acids | LONZA AG (CH) | 1993-09-08 | — | — | EP | claimed |
| CN-1237051-C | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGRO SCIENCES LLC (US) | 2006-01-18 | — | — | CN | disclosed |
| CN-1208321-C | Fungicidal heterocyclic aromatic amides and their compositions methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2005-06-29 | — | — | CN | disclosed |
| CN-1450993-A | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2003-10-22 | — | — | CN | disclosed |
| CN-1390204-A | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGRO SCIENCES LLC (US) | 2003-01-08 | — | — | CN | disclosed |
| WO-2002029021-A2 | BIOTECHNOLOGICAL METHOD FOR PREPARING CARBOXYLIC ACIDS WITH A HYDROXY-NITROGEN HETEROCYCLE | LONZA AG (CH) | 2002-04-11 | — | — | WO | disclosed |
| EP-0559116-B1 | Microbiological process for the hydroxylation of nitrogen containing heterocyclic carbonic acids | LONZA AG (CH) | 1997-05-28 | — | — | EP | disclosed |
| US-5364940-A | For treatment of sewage sludge with cultures | LONZA LTD. (CH) | 1994-11-15 | — | — | US | disclosed |
| US-5306630-A | Microbiological process for hydroxylation of nitrogen-heterocyclic-carboxylic acids | LONZA LTD. (CH) | 1994-04-26 | — | — | US | disclosed |
| CN-1077748-A | With microbial process the nitrogen heterocyclic ring carboxylic acid is carried out hydroxylation | LONZA AG (CH) | 1993-10-27 | — | — | CN | disclosed |
| EP-0559116-A2 | Microbiological process for the hydroxylation of nitrogen containing heterocyclic carbonic acids | LONZA AG (CH) | 1993-09-08 | — | — | EP | disclosed |