Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537410 | 0.96 | MAPT (0.47) | MAPTSMN1; SMN2TP53KDRFLT1 | |
| SCHEMBL7532056 | 0.81 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2TP53KDRFLT1 | |
| SCHEMBL7533716 | 0.81 | KDR (0.45) | F10MAPTSMN1; SMN2KDRMEN1 | |
| SCHEMBL7534225 | 0.81 | HTT (0.53) | MAPTSMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL7537216 | 0.78 | ALDH1A1 (0.58) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL7531353 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL7531734 | 0.77 | DHODH (0.49) | MAPTSMN1; SMN2LMNAPOLBHTT | |
| 3-Chloroaniline SCHEMBL7533700 | 0.76 | CYP1A2 (0.48) | MAPTSMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL7533699 | 0.76 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2TP53KDRFLT1 | |
| SCHEMBL7533037 | 0.75 | HTT (0.55) | MAPTSMN1; SMN2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |